Figure 3.

Anti-nuclear antibody (ANA) and anti-dsDNA levels in 21 falciparum-infected children before and seven days after SP treatment and in age-matched uninfected children. Samples from the infected children (A and B, Pre-Rx and Post-Rx) were collected during the season of high transmission. The Pre-Rx samples in (A) and (B) were collected before SP treatment. The Post-Rx samples in (A) and (B) were collected seven days after SP treatment. Samples from children exhibiting no evidence of falciparum infection were collected during a season of low transmission (A, LT). ANA Index values were calculated according to assay kit instructions and interpreted as negative, ≤0.90; equivocal, 0.91-1.09; and positive, ≥1.10. Anti-dsDNA levels were calculated according to assay kit instructions and interpreted as negative <25 IU/ml, borderline positive: 25-30 IU/ml, positive: 60-200 IU/ml, and high positive: >200 IU/ml.