Table 6

The pvdhfr/pvdhps genotypes and therapeutic responses of 15 patients from Tsiroanomandidy (Madagascar, 2006) treated with sulphadoxine-pyrimethamine for P. vivax infections

Sequence polymorphism in

Patient

pvdhfr

Pvdhps

No. of mutations in the 2 genes

Therapeutic response^b

Trial no.

Age (Years)

33

58

117

383

VIV7

2

P

S

S

A

0

ACPR

60446

2.5

P

S

S

A

0

ACPR

VIV14

7

L

S

S

A

1

ACPR

VIV18

13

P

S

S

A

0

ACPR

60756

42

P

S

S

A

0

ACPR

VIV3

12

P

R

N

G

3

ACPR

VIV8

34

P

S

N

A

1

ACPR

VIV20

9

P

R

N

A

2

TF

62298

5

P

R

N

A

2

ACPR

60250

6

P

R

N

A

2

ACPR

60149

8

P

R

N

G

3

ACPR

VIV4

30

P

R

N

G

3

ACPR

VIV12

6

P

R

N

G

3

TF

62079

0.8

P

R

N

A

2

TF

VIV15

2

P

R

N

A

2

Reinfection or relapse

Barnadas et al. Malaria Journal 2008 7:35   doi:10.1186/1475-2875-7-35