Malaria Journal

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Why don't health workers prescribe ACT? A qualitative study of factors affecting the prescription of artemether-lumefantrine

Beatrice Wasunna*, Dejan Zurovac, Catherine A Goodman and Robert W Snow

Malaria Journal 2008, 7:29 doi:10.1186/1475-2875-7-29

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BioMed Central: 14 citations

Research   Open Access

Prescription practices and availability of artemisinin monotherapy in India: where do we stand?

Neelima Mishra, Anupkumar R Anvikar, Naman K Shah, Vineet Kumar Kamal, Surya Kant Sharma, Harish Chandra Srivastava, Manoj Kumar Das, Khageswar Pradhan, Hemant Kumar, Yogendra K Gupta, Pooja Gupta, Aditya Prasad Dash, Neena Valecha Malaria Journal 2011, 10:360 (13 December 2011)

This paper reports the findings for a study carried out in India in 2008 which aimed to document the availability of and prescription practices with regards anti-malarial drugs and in particular artemisinin monotherapy. This is an important topic given India¿s geographically strategic location, lying between the epicentre of artemisinin resistance on the Thai-Cambodia border to the East ¿ and the continent of Africa to the West. The key finding are very concerning and it is reassuring that some action has apparently taken place since the study took place.

Research   Open Access

Management of uncomplicated malaria in children under 13 years of age at a district hospital in senegal: from official guidelines to usual practices

Sophie Sarrassat, Richard Lalou, Moustapha Cissé, Jean-Yves Le Hesran Malaria Journal 2011, 10:285 (29 September 2011)

The paper describes a retrospective study of hospital records of children aged 2months to 13 years seen at a hospital in Senegal in 2004 and 2005. Data are presented for treatments given to febrile, non-febrile, tested, untested patients and patients with unknown temperature.

Research   Open Access

Adherence to prescribed artemisinin-based combination therapy in Garissa and Bunyala districts, Kenya

Harriet Lawford, Dejan Zurovac, Laura O'Reilly, Sarah Hoibak, Alice Cowley, Stephen Munga, John Vulule, Elizabeth Juma, Robert W Snow, Richard Allan Malaria Journal 2011, 10:281 (23 September 2011)

In the perspective of the present deployment of ACT in Africa and the risk of emergence of resistance to these combinations, the paper addresses the important topic of how to influence adherence to treatment.

Research   Open Access Highly Accessed

Saleability of anti-malarials in private drug shops in Muheza, Tanzania: a baseline study in an era of assumed artemisinin combination therapy (ACT)

Frank M Ringsted, Isolide S Massawe, Martha M Lemnge, Ib C Bygbjerg Malaria Journal 2011, 10:238 (15 August 2011)

Paper looking at the reality of access to treatment in rural Africa: 3/4 cases of suspected malaria were treated in the private sector, and 9/10 obtained SP or AQ. Hence, a majority of clinical malaria cases in the community, failed to get treated in accordance with national guidelines.

Review   Open Access

Taking stock: provider prescribing practices in the presence and absence of ACT stock

Bernadette Hensen, Lucy Paintain, Rima Shretta, Jane Bruce, Caroline Jones, Jayne Webster Malaria Journal 2011, 10:218 (3 August 2011)

An important paper in its field addressing relation between anti-malarial prescribing behaviour and ACT stock-out on six studies where some data on this topic are available. The paper concludes that stock outs influence behaviour and rightly call for revival of facility-based quality of care surveys, an activity largely forgotten within most of the control programmes.

Research   Open Access

Changes in health workers' malaria diagnosis and treatment practices in Kenya

Elizabeth Juma, Dejan Zurovac Malaria Journal 2011, 10:1 (7 January 2011)

This article is part of a collection on National malaria control...

There is presently no contention that prompt and effective malaria case management can reduce malaria mortality. However, the symptoms of non-complicated malaria are non-specific and similar to many other disease syndromes. High sensitivity of malaria diagnosis is crucial in all epidemiological settings, but high specificity, especially in low transmission settings, is likely to reduce non-necessary malaria treatment and improve the diagnosis of other febrile illness.

Research   Open Access

Improvements in access to malaria treatment in Tanzania after switch to artemisinin combination therapy and the introduction of accredited drug dispensing outlets - a provider perspective

Sandra Alba, Manuel W Hetzel, Catherine Goodman, Angel Dillip, Jafari Liana, Hassan Mshinda, Christian Lengeler Malaria Journal 2010, 9:164 (15 June 2010)

The public health and private retail sector are important complementary sources of treatment in rural Tanzania. Ensuring the availability of ACT in the private retail sector is important for its successful uptake.

Research   Open Access Highly Accessed

Barriers to prompt and effective malaria treatment among the poorest population in Kenya

Jane Chuma, Vincent Okungu, Catherine Molyneux Malaria Journal 2010, 9:144 (27 May 2010)

Evidence suggests that the poorest populations benefit less from malaria control interventions, and are less likely to seek prompt and effective treatment.

Review   Open Access

Reviewing the literature on access to prompt and effective malaria treatment in Kenya: implications for meeting the Abuja targets

Jane Chuma, Timothy Abuya, Dorothy Memusi, Elizabeth Juma, Willis Akhwale, Janet Ntwiga, Andrew Nyandigisi, Gladys Tetteh, Rima Shretta, Abdinasir Amin Malaria Journal 2009, 8:243 (28 October 2009)

This review on access to malaria treatment in Kenya is particularly interesting in the light of the wealth of studies that have been carried out on related topics in Kenya.

Research   Open Access Highly Accessed

Physical and chemical stability of expired fixed dose combination artemether-lumefantrine in uncontrolled tropical conditions

Roger Bate, Richard Tren, Kimberly Hess, Amir Attaran Malaria Journal 2009, 8:33 (25 February 2009)

The data indicate that existing fixed-dose combinations are chemically and physically stable well beyond their stated shelf-life in uncontrolled, tropical conditions. This strongly suggests that a re-evaluation of the two-year shelf-life by drug regulatory authorities is warranted.

Research   Open Access

A randomized, open-label, comparative efficacy trial of artemether-lumefantrine suspension versus artemether-lumefantrine tablets for treatment of uncomplicated Plasmodium falciparum malaria in children in western Kenya

Elizabeth A Juma, Charles O Obonyo, Willis S Akhwale, Bernhards R Ogutu Malaria Journal 2008, 7:262 (22 December 2008)

The limitations of administering hard tablets to young children have motivated this study: the two formulations appear to be comparable

Review   Open Access Highly Accessed

Deployment of ACT antimalarials for treatment of malaria: challenges and opportunities

Christopher JM Whitty, Clare Chandler, Evelyn Ansah, Toby Leslie, Sarah G Staedke Malaria Journal 2008, 7(Suppl 1):S7 (11 December 2008)

Research   Open Access

Malaria case-management under artemether-lumefantrine treatment policy in Uganda

Dejan Zurovac, James K Tibenderana, Joan Nankabirwa, James Ssekitooleko, Julius N Njogu, John B Rwakimari, Sylvia Meek, Ambrose Talisuna, Robert W Snow Malaria Journal 2008, 7:181 (19 September 2008)

The paper provides a large cross-sectional survey of malaria treatment practices at clinics from four regions of Uganda representing different epidemiologic situations. The study offers a valuable snapshot of the status of malaria care at clinics in Uganda about a year after the country rolled out their new national regimen for the treatment of uncomplicated malaria.

Research article   Open Access

A qualitative study of the feasibility and community perception on the effectiveness of artemether-lumefantrine use in the context of home management of malaria in south-west Nigeria

Ikeoluwapo O Ajayi, Catherine O Falade, Benjamin O Olley, Bidemi Yusuf, Sola Gbotosho, Toyin Iyiola, Omobola Olaniyan, Christian Happi, Kaendi Munguti, Franco Pagnoni BMC Health Services Research 2008, 8:119 (1 June 2008)