Malaria Journal

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A randomized trial on effectiveness of artemether-lumefantrine versus artesunate plus amodiaquine for unsupervised treatment of uncomplicated Plasmodium falciparum malaria in Ghanaian children

Robin Kobbe1,6*, Philipp Klein1, Samuel Adjei2,3, Solomon Amemasor4, William N Thompson4, Hanna Heidemann1, Maja V Nielsen1, Julia Vohwinkel1, Benedikt Hogan1, Benno Kreuels1,7, Martina Bührlen4, Wibke Loag1, Daniel Ansong5 and Jürgen May1

Author Affiliations

1 Infectious Disease Epidemiology, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany

2 Ministry of Health/Ghana Health Service, District Health Directorate, Agona, Afigya Sekyere District, Ghana

3 Kumasi Centre for Collaborative Research in Tropical Medicine, Kumasi, Ghana

4 Agogo Presbyterian Hospital, Agogo, Asante Akim North District, Ghana

5 Department of Child Health, School of Medical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana

6 Department of Paediatrics, University Medical Centre Eppendorf, Hamburg, Germany

7 Section for Tropical Medicine, Bernhard Nocht Clinic, University Medical Centre Eppendorf, Hamburg, Germany

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Malaria Journal 2008, 7:261 doi:10.1186/1475-2875-7-261

Published: 19 December 2008

Additional files

Additional file 1:

Questions asked after completion of the 3-day treatment course to evaluate treatment acceptance of ASAQ and AL. Answers of parents/guardians were scored with 1 point (difficult/bad), 2 (fairly difficult/fair), 3 (easy/good), or 4 (very easy/very good) points, and were compared using Wilcoxon rank sum tests.

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