Table 1 |
||||
|
Genotype frequency distribution of SNPs in patient and control groups |
||||
| Gene name |
SNP |
Control (n = 192) |
Non-severe (n = 89) |
Severe (n = 93) |
|
|
||||
| ICAM1 |
Ex6 (rs5498) |
|||
| AA |
70 (36.5%) |
17 (19.1%) |
21 (22.5%) |
|
| AG |
93 (48.4%) |
46 (51.7%) |
42 (45.2%) |
|
| GG |
29 (15.1%) |
26 (29.2%) |
30 (32.3%) |
|
|
|
||||
| PECAM1 |
Ex3 (rs668) |
|||
| CC |
108 (56.3%) |
39 (43.8%) |
43 (46.2%) |
|
| CG |
53 (27.6%) |
36 (40.4%) |
40 (43%) |
|
| GG |
31 (16.1) |
14 (15.7%) |
10 (10.8%) |
|
|
|
||||
| Ex8 (rs12953) |
||||
| GG |
80 (41.7%) |
30 (33.7%) |
40 (43%) |
|
| AG |
76 (39.5) |
40 (44.9%) |
32 (34.4%) |
|
| AA |
36 (18.8%) |
19 (21.3%) |
21 (22.6%) |
|
|
|
||||
| Ex12 (rs1131012) |
||||
| AA |
69 (35.9%) |
28 (31.4%) |
41 (44.1%) |
|
| AG |
101 (52.6%) |
43 (48.3%) |
34 (36.6%) |
|
| GG |
22 (11.5%) |
18 (20.2%) |
18 (19.3%) |
|
|
|
||||
| CD36 |
-14 (rs2151916) |
|||
| TT |
83 (43.2%) |
31 (34.8%) |
38 (40.9%) |
|
| TC |
76 (39.6%) |
42 (47.2%) |
38 (40.9%) |
|
| CC |
33 (17.2%) |
16 (18%) |
17 (18.2%) |
|
|
|
||||
| -53 (rs1334512) |
||||
| GG |
61 (31.8%) |
34 (38.2%) |
47 (50.5%) |
|
| GT |
87 (45.3%) |
36 (40.4%) |
32 (34.4%) |
|
| TT |
44 (22.9%) |
19 (21.3%) |
14 (15.1%) |
|
|
|
||||
| Ex1a |
||||
| TT |
115 (59.9%) |
42 (47.2%) |
38 (40.9%) |
|
| TA |
59 (30.7%) |
32 (36%) |
30 (32.2%) |
|
| AA |
18 (9.4%) |
15 (16.8%) |
25 (26.9%) |
|
|
|
||||
|
Sinha et al. Malaria Journal 2008 7:250 doi:10.1186/1475-2875-7-250 |
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