Malaria Journal

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Open Access

The content of African diets is adequate to achieve optimal efficacy with fixed-dose artemether-lumefantrine: a review of the evidence

Zulfiqarali G Premji*, Salim Abdulla, Bernhards Ogutu, Alice Ndong, Catherine O Falade, Issaka Sagara, Nathan Mulure, Obiyo Nwaiwu and Gilbert Kokwaro

Malaria Journal 2008, 7:244 doi:10.1186/1475-2875-7-244

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Research   Open Access

Similar efficacy and safety of artemether-lumefantrine (Coartem(R)) in African infants and children with uncomplicated falciparum malaria across different body weight ranges

Quique Bassat, Raquel Gonzalez, Sonia Machevo, Alain Nahum, John Lyimo, Hamma Maiga, Andreas Martensson, Mahfudh Bashraheil, Peter Ouma, David Ubben, Verena Walter, Obiyo Nwaiwu, Chemtai Kipkeu, Gilbert Lefevre, Bernhards Ogutu, Clara Menendez Malaria Journal 2011, 10:369 (16 December 2011)

The study investigates the impact of different weight bands on treatment outcome after AL treatment. There has been some concern that the dosing optimization according weight bands may result in over dosing young children and under dosing older children. Therefore this study and the findings are very important for malaria endemic countries that have adopted AL as the first-line regimen.

Review   Open Access

Understanding the pharmacokinetics of Coartem®

Abdoulaye Djimdé, Gilbert Lefèvre Malaria Journal 2009, 8(Suppl 1):S4 (12 October 2009)