Table 1

Summary of field isolate studies of clumping and malaria severity.

Study
Site
Haematocrit
Parasitaemia
Time (min)
Significant association of clumping with:

Pain et al 2001 [6]
Kenya
5%
variable
15, 30, 60, 120
Severe malaria (impaired consciousness, respiratory distress, Hb < 5 g/dl)
Chotivanich et al 2004 [7]
Thailand
1%
variable
15
Cerebral malaria and parasitaemia but not other forms of severe malaria (mostly multi-organ failure)
Arman et al 2007 [8]
Mali
2%
variable
30
Parasitaemia but not severe disease
Wassmer et al 2008 [10]
Malawi
5%
Adjusted to 10%
15, 30, 60, 120
Cerebral malaria and severe malarial anaemia

Arman and Rowe Malaria Journal 2008 7:243   doi:10.1186/1475-2875-7-243

Open Data