Table 5 |
|||
|
SNPs and amino-acids changes in aldolases and pLDHs in P. falciparum and P. vivax isolates collected in Madagascar in 2006, from different geographic areas. |
|||
| Genes |
SNP (bp position and change) |
Amino acid change (aa position and change) |
Frequency No (%) |
|
|
|||
| P. falciparum aldolase |
815 (CAC to CGC) |
104 (H to R) |
2 (0.8) |
| 1314 (CCA to CCC) |
synonymous change |
1 (0.4) |
|
| 1404 (CAC to CAG) |
300 (H to Q) |
2 (0.8) |
|
| 1417 (ACC to GCC) |
305 (T to A) |
1 (0.4) |
|
|
|
|||
| P. vivax aldolase |
510 (TCC to TCA) |
synonymous change |
1 (0.9) |
| 651 (TTA to TTG) |
synonymous change |
43 (39.1) |
|
|
|
|||
| P. falciparum LDH |
73 (CAG to AAG) |
25 (Q to K) |
1 (0.7) |
| 814 (GAT to AAT) |
272 (D to N) |
10 (7.3) |
|
|
|
|||
| P. vivax LDH |
168 (ATG to ATA) |
56 (D to N) |
1 (0.9) |
| 225 (AAG to AAA) |
synonymous change |
84 (75.7) |
|
| 405 (ATC to ATT) |
synonymous change |
2 (1.8) |
|
| 498 (GTC to GTT) |
synonymous change |
1 (0.9) |
|
| 544 (GTT to ATT) |
182 (V to I) |
1 (0.9) |
|
| 627 (GTG to GTC) |
synonymous change |
32 (28.8) |
|
| 687 (GCC to GCT) |
synonymous change |
23 (20.7) |
|
|
|
|||
|
Mariette et al. Malaria Journal 2008 7:219 doi:10.1186/1475-2875-7-219 |
|||
