Table 3

Observed versus expected heteroxygosity in the study populations.



IAM
SMM






Population
No. of loci
H excess
H deficiency
P
H excess
H deficiency
P
Mode- shift

Severe malaria
12
8
4
NS
5
7
NS
normal
Uncomplicated malaria
12
6
6
NS
2
10
P < 0.05
normal

Proportion of loci with excessive or deficient observed heterozygosities, relative to expected heterozygosities. Data were subject to mutation drift equilibrium via IAM and SMM, as well as mode-shift analyses. H: heterozygosity. NS: not significant.

Susomboon et al. Malaria Journal 2008 7:212   doi:10.1186/1475-2875-7-212

Open Data