|
Paired analysis of haematological parameters: booking consultation (healthy) and at the first episode of malaria |
||||||
| Species (N) |
Parameter |
Median |
min |
max |
P* |
|
|
|
||||||
| P. falciparum (N = 24) |
Platelet |
Baseline (healthy)/μL |
256,000 |
115,000 |
419,000 |
< 0.001 |
| Reduction from baseline/μL |
-86,000 |
-305,000 |
-5,000 |
|||
| % difference (95%CI) |
-34 (-24 to -47)% |
|||||
| Haemoglobin |
Baseline (healthy) g/dL |
11.2 |
9.9 |
14.2 |
0.005 |
|
| Reduction from baseline g/dL |
-0.3 |
-3.3 |
1.9 |
|||
| % difference (95%CI) |
-3 (-2 to -4)% |
|||||
| WBC |
Baseline (healthy)/μL |
9,900 |
4,500 |
13,900 |
0.070 |
|
| Reduction from baseline/μL |
-1,250 |
-6,400 |
3,100 |
|||
| % difference (95%CI) |
-13 (-9 to -18)% |
|||||
| P. vivax (N = 36) |
Platelet |
Baseline (healthy)/μL |
242,000 |
101,000 |
438,000 |
< 0.001 |
| Reduction from baseline/μL |
-52.5 |
-376 |
129 |
|||
| % difference (95%CI) |
-22 (-16 to -29)% |
|||||
| Haemoglobin |
Baseline (healthy) g/dL |
11.4 |
8.9 |
12.9 |
0.031 |
|
| Reduction from baseline g/dL |
-0.6 |
-2.4 |
1.2 |
|||
| % difference (95%CI) |
-5 (-4 to -7)% |
|||||
| WBC |
Baseline (healthy)/μL |
8,900 |
1,300 |
24,00 |
< 0.001 |
|
| Reduction from baseline/μL |
-750 |
-16,600 |
11,800 |
|||
| % difference (95%CI) |
-8 (-6 to -12)% |
|||||
|
*P paired analysis of reduction from baseline | ||||||
Tan et al. Malaria Journal 2008 7:209 doi:10.1186/1475-2875-7-209 |
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