Table 3 |
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|
Reinfection risk of untreated children during 61 days after scheduled time of IPTi application |
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|
Eventa |
IPTi-1 |
IPTi-2 |
IPTi-3 |
|||
|
|
||||||
|
n |
% (CI) |
n |
% (CI) |
n |
% (CI) |
|
|
|
||||||
|
Kumasi |
n = 449 |
n = 428 |
n = 368 |
|||
|
Parasitaemia |
90 |
20.0 (16.4–24.1) |
107 |
25.0 (21.0–29.4) |
111 |
30.2 (25.5–35.1) |
|
Asymptomatic |
66 |
14.6 (11.6–18.3) |
62 |
14.5 (11.3–18.2) |
61 |
16.6 (12.9–20.8) |
|
Symptomatic |
24 |
5.4 (3.5–7.8) |
45 |
10.5 (7.8–13.8) |
50 |
13.6 (10.3–17.5) |
|
Lambaréné |
n = 484 |
n = 412 |
n = 317 |
|||
|
Parasitaemia |
3 |
0.6 (0.1–1.8) |
12 |
2.9 (1.5–5.0) |
3 |
1.0 (0.2–2.7) |
|
Asymptomatic |
1 |
0.2 (0.0–1.1) |
1 |
0.2 (0.0–1.3)b |
0 |
0.0 (0.0–1.2)b |
|
Symptomatic |
2 |
0.4 (0.1–1.5) |
11 |
2.7 (1.3–4.7) |
3 |
1.0 (0.2–2.7) |
|
|
||||||
|
CI, 95% confidence interval. Denominator is the number of children from the placebo group without parasitaemia at scheduled time of IPTi application and with at least one available parasite assessment during the 61 days after IPTi application. The difference between the proportion of infected individuals in Kumasi and Lambaréné was always significant with at least p < 0.0001. a Nominators are number of events during 61 days after scheduled time of IPTi application. b One-sided, 97.5% confidence interval. |
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|
May et al. Malaria Journal 2008 7:198 doi:10.1186/1475-2875-7-198 |
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