Table 3 |
||||||||||||
|
Symptoms and clinical signs |
||||||||||||
| Drug Group |
Quinine |
Atovaquone-proguanil |
Artemether-lumefantrine |
|||||||||
|
|
||||||||||||
| n = |
30 |
30 |
30 |
23 |
30 |
30 |
30 |
26 |
30 |
30 |
30 |
28 |
| day |
0 |
7 |
28 |
90 |
0 |
7 |
28 |
90 |
0 |
7 |
28 |
90 |
| Hearing Problem |
0 |
9 |
1 |
0 |
0 |
1 |
0 |
1 |
1 |
2 |
1 |
0 |
| Tinnitus |
2 |
8 |
3 |
0 |
4 |
6 |
1 |
1 |
6 |
4 |
2 |
0 |
| Vertigo |
6 |
0 |
1 |
0 |
8 |
1 |
0 |
0 |
4 |
3 |
1 |
0 |
| Imbalance |
1 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
| Spontaneous nystagmus |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
| Provoked nystagmus |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
| Pathologic head rotation test |
1 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
1 |
0 |
0 |
0 |
| Impaired coordination |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
| Fever |
24 |
0 |
5 |
2 |
23 |
2 |
3 |
1 |
26 |
0 |
1 |
2 |
| Shivering |
23 |
0 |
1 |
2 |
26 |
4 |
3 |
1 |
21 |
1 |
1 |
1 |
| Headache |
30 |
5 |
5 |
2 |
30 |
10 |
6 |
3 |
30 |
7 |
4 |
2 |
| Nausea |
21 |
1 |
2 |
0 |
17 |
1 |
1 |
0 |
22 |
0 |
0 |
4 |
| Diarrhea |
4 |
0 |
0 |
0 |
2 |
1 |
1 |
0 |
3 |
0 |
0 |
0 |
| Vomiting |
1 |
0 |
0 |
0 |
1 |
0 |
0 |
0 |
1 |
0 |
0 |
0 |
| Anorexia |
2 |
0 |
1 |
0 |
3 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
| Abdominal pain |
1 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
1 |
0 |
0 |
0 |
| Arthralgia |
3 |
0 |
0 |
0 |
3 |
0 |
0 |
0 |
1 |
0 |
0 |
0 |
| Myalgia |
1 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
| Chest pain |
0 |
0 |
0 |
0 |
0 |
1 |
0 |
0 |
0 |
0 |
0 |
0 |
| Cough |
0 |
1 |
0 |
0 |
0 |
1 |
0 |
0 |
0 |
0 |
0 |
0 |
|
|
||||||||||||
|
Gürkov et al. Malaria Journal 2008 7:179 doi:10.1186/1475-2875-7-179 |
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