Differences in Fcgamma receptor IIa genotypes and IgG subclass pattern of anti-malarial antibodies between sympatric ethnic groups in Mali
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* Corresponding author: Klavs Berzins klavs@imun.su.se
Malaria Journal 2008, 7:175 doi:10.1186/1475-2875-7-175
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Research
Elisabeth Israelsson, Mattias Ekström, Amre Nasr, Amagana Dolo, Susannah Kearsley, Gishanthi Arambepola, Manijeh Homann, Bakary Maiga, Ogobara K Doumbo, Gehad ElGhazali, Hayder A Giha, Marita Troye-Blomberg, Klavs Berzins, Per Tornvall Malaria Journal 2009, 8:136 (22 June 2009) The frequency of the CRP-286A allele, which correlates with high levels of serum CRP, is lower in Fulani, an ethnic group with low susceptibility to malaria. This could be a selective advantage in fighting malaria infection.
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Research
Amre Nasr, Nnaemeka C Iriemenam, Hayder A Giha, Halima A Balogun, Robin F Anders, Marita Troye-Blomberg, Gehad ElGhazali, Klavs Berzins Malaria Journal 2009, 8:43 (13 March 2009) This study confirms and extends previous findings analysing the polymorphism in relation to the IgG subclass distribution seen among two sympatric tribes living in eastern Sudan and coincidental with marked differences in susceptibility to falciparum malaria.
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