Table 2 |
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|
Comparison of αMSP1-19kD IgG responses with malaria infection status during community surveys. |
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| Malaria status |
Age group |
N (n < neg cut-off, n > 3* neg cut-off) |
Median |
Lower quartile |
Upper quartile |
p (WRS test) |
|
|
||||||
| PF |
Adults |
14 (1, 14) |
1.446 |
1.141 |
1.851 |
0.3132 |
| PF |
Children |
14 (3, 8) |
1.339 |
0.740 |
1.803 |
|
| NEG |
Adults |
433 (141, 227) |
1.040 |
0.505 |
1.562 |
<0.0001 |
| NEG |
Children |
435 (302, 89) |
0.301 |
0.161 |
0.827 |
|
|
|
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|
In adults, P. falciparum infected, P. vivax infected, and Plasmodium-negative (NEG) individuals had similar αMSP1-19kD IgG OD levels. The low αMSP1-19kD response frequency in NEG children suggests that fewer children had prior P. falciparum infection which could explain the maintained αMSP1-19kD antibody response seen in adults. |
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|
Torres et al. Malaria Journal 2008 7:173 doi:10.1186/1475-2875-7-173 |
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