Table 1 |
|||
|
N-Glycosylation sites mutated in HEK293 expressed DBL domains |
|||
| Domains |
Boundaries |
N-Glycosylation sites mutated* |
|
|
|
|||
| DBL1-x |
58 – 383 |
5 |
N85I |
| N147Q |
|||
| N356K |
|||
| N362H |
|||
| N380Q |
|||
|
|
|||
| DBL2-x |
530 – 863 |
2 |
N692Q |
| N730Q |
|||
|
|
|||
| DBL3-x |
1221 – 1548 |
3 |
N1222S |
| N1290Q |
|||
| N1428K |
|||
|
|
|||
| DBL4-ε |
1594 – 1888 |
4 |
N1674H |
| N1744Q |
|||
| N1749Q |
|||
| N1844Q |
|||
|
|
|||
| DBL5-ε |
2003 – 2270 |
3 |
N2134Q |
| N2210Q |
|||
| N2223Q |
|||
|
|
|||
| DBL6-ε |
2322 – 2590 |
2 |
N2442Q |
| N2537Q |
|||
|
|
|||
|
*Asparagine residues were changed to glutamine or, in some instances, to amino acids found in other var2csa alleles at this location. |
|||
|
Fernandez et al. Malaria Journal 2008 7:170 doi:10.1186/1475-2875-7-170 |
|||
