Table 3

Activity of esterases, glutathione S-transferases and monooxygenases in Anopheles culicifacies and Anopheles subpictus populations (n > 200 for each value)

Anuradhapura
 Kurunegala
 Moneragala
 Puttalam
 Trincomalee


Ac
 As
 Ac
 As
 Ac
 As
 Ac
 As
 Ac
 As
Est1
 52
 10
 51
 18
 44
 21
 30
 17
 15
 06
GST2
 28
 19
 13
 26
 10
 43
 36
 45
 60
 09
MO3
 24
 38
 38
 28
 56
 27
 27
 20
 72
 86
MCE4
 +
 +
 -
 ++
 +++
 +++
 +
 +
 +++
 +++

Ac = An. culicifacies

As = An. subpictus

1. % population having esterase specific activity above 0.25 μmol/mg/min

2. % population having glutathione S-transferase specific activity above 0.40 μmol/mg/min

3. % population having monooxygenase levels above 0.35 equivalent units of cytochrome P450

4. malathion carboxylesterase activity as measured by malathion metabolism studies (see text for details)

- no activity ++ – moderate +++ – high

Perera et al. Malaria Journal 2008 7:168   doi:10.1186/1475-2875-7-168

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