Table 2

Day 28 failure rates estimated by four methods – AS+AQ treatment



Day 28 failure rates
% [CI95%]


Year
 Country &
Site
 Method 1a
(per protocol)
 Method 1b
 Method 2a
(WHO 2001)
 Method 2b
2003
 Angola, Kuito
 1.3
 1.2
 1.2
 1.2


[0–6.8]
 [0–6.4]
 [0.2–8.3]
 [0.2–8.1]
2003
 DRC, Boende
 18.3
 14.1
 15.3
 56.3


[9.5–30.4]
 [7.2–23.8]
 [8.7–25.9]
 [45.8–67.4]
2003
 S Sudan, Nuba
 7.3
 5.6
 6.2
 8.4


[2.0–17.6]
 [1.5–12.6]
 [2.4–15.7]
 [3.9–18.0]
2003
 Uganda, Amudat
 22.6
 8.8
 10.4
 21.4


[9.6–41.1]
 [3.6–17.2]
 [4.9–21.1]
 [14.0–31.8]
2003
 Uganda, Jinja
 7.9
 6.5
 7.0
 12.2


[3.2–15.7]
 [2.7–13.0]
 [3.4–14.1]
 [7.2–20.1]
2003
 Uganda, Kampala
 4.9
 4.1
 4.3
 4.3


[1.0–13.7]
 [0.9–11.5]
 [1.4–12.8]
 [1.4–12.9]
2004
 Angola, Caala
 0
 0
 0
 1.5


[0–6.0]*
 [0–5.7]*
 [0–5.8]*
 [0.2–10.4]
2004
 Congo, Kindamba
 6.0
 4.8
 4.8
 6.4


[1.6–14.6]
 [1.3–11.9]
 [1.8–12.2]
 [2.9–13.7]
2004
 DRC, Kabalo
 0
 0
 0
 4.4


[0–8.4]*
 [0–7.9]*
 [0–7.9]*
 [1.1–16.3]
2004
 Guinea, Dabola
 1.0
 0.9
 0.9
 0.9


[0–5.3]
 [0–5.1]
 [0.1–6.5]
 [0.1–6.5]
2004
 S Leone, Kailahun
 27.0
 15.4
 19.0
 20.5


[16.6–39.6]
 [9.3–23.6]
 [12.3–28.8]
 [13.5–30.5]
2004
 Uganda, Apac
 24.5
 15.0
 15.7
 15.9


[16.2–34.4]
 [9.8–21.7]
 [10.7–22.7]
 [10.8–23.1]
2004
 Uganda, Arua
 28.7
 19.9
 20.0
 20.0


[20.4–38.2]
 [13.9–27.0]
 [14.5–27.2]
 [14.6–27.0]
2004
 Uganda, Tororo
 39.3
 14.5
 17.8
 20.0


[27.1–52.7]
 [9.5–20.9]
 [12.1–25.8]
 [13.6–28.9]
2005
 Uganda, Tororo
 13.9
 5.5
 5.4
 5.9


[6.9–24.1]
 [2.6–9.8]
 [2.9–9.8]
 [3.3–10.4]

*one-sided 97.5% CIs

Ashley et al. Malaria Journal 2008 7:154   doi:10.1186/1475-2875-7-154

Open Data