Table 4 |
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|
Prevalence and levels of antibodies to the OR domain of the P. falciparum P126 protein in Candeias do Jamari and Peixoto de Azevedo groups according to the infection patterns. |
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|
Infection |
IgG |
IgM |
IgG1 |
IgG2 |
IgG3 |
IgG4 |
|
|
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|
Candeias do Jamari (CJ) |
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|
|
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|
OR-II |
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|
CJ-1993 |
47/69 (68) 4.9 ± 3.0d |
39/63 (62) 3.4 ± 2.1 |
39/44a(88) 3.2 ± 2.1e |
6/44b(13) 3.1 ± 2.9 |
42/44c(95) 10.6 ± 10.0 |
19/44 (43) 1.6 ± 0.7f |
|
CJ-2002 |
55/70 (78) 8.4 ± 8.2j |
57/70g (81) 4.8 ± 4.8 |
13/55h (23) 1.9 ± 0.7 |
19/55i(34) 1.3 ± 0.4 |
35/55 (60) 7.5 ± 6.1 |
23/55 (42) 2.6 ± 2.2k |
|
|
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|
Peixoto de Azevedo (PA) |
||||||
|
|
||||||
|
OR-I |
19/25 (76) 4.9 ± 2.9 |
13/25 (52) 1.7 ± 0.9 |
13/18l (72) 2.0 ± 1.8 |
0/18m - |
18/18n (100) 9.8 ± 6.8 |
9/18 (50) 1.4 ± 0.2 |
|
OR-II |
36/46 (78) 4.3 ± 2.7 |
27/46 (59) 2.7 ± 1.7 |
21/36o (58) 2.1 ± 1.7 |
5/36p (14) 1.3 ± 0.4 |
34/36q (94) 7.6 ± 6.1 |
16/36 (44) 1.3 ± 0.1 |
|
Mixed |
16/19 (84) 4.5 ± 3.1 |
9/19 (47) 2.0 ± 1.4 |
11/16r(69) 2.9 ± 2.7 |
0/16s - |
16/16 (100)t 7.5 ± 6.4 |
5/16 (31) 1.3 ± 0.1 |
|
|
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|
The data represent the number of responders/total of each fragment tested (the percentage of responders is given in parentheses) and the antibody levels expressed as mean of OD index ± SD. P < 0.05. a: CJ-1993- IgG1 > IgG2, IgG1 > IgG4; CJ-1993 IgG1 > CJ-2002 IgG1; b: CJ-1993- IgG2 < IgG3, IgG2 < IgG4; CJ-1993 IgG2 < CJ-2002 IgG2; c: CJ-1993- IgG3 > IgG4; CJ-1993 IgG3 > CJ-2002 IgG3; d: CJ-1993 IgG < CJ-2002 IgG; e: CJ-1993 IgG1 > CJ-2002 IgG1; f: CJ-1993 IgG4 < CJ-2002 IgG4; g: CJ-2002 IgM > CJ-1993 IgM, CJ-2002 IgM > PA IgM; h: CJ-2002 IgG1 < IgG3; i: CJ-2002 IgG2 < IgG3; CJ-2002 IgG2 > PA OR-II IgG2; j: CJ-2002 IgG > PA OR-II IgG; k: CJ-2002 IgG4 > PA OR-II IgG4 l: PA OR-I IgG1 > IgG2; PA OR-I IgG1 < IgG3; m: PA OR-I IgG2 < IgG3; PA OR-I IgG2 < IgG4; n: PA OR-I IgG3 > IgG4; o: PA OR-II IgG1 > IgG2; PA OR-II IgG1 < IgG3; p: PA OR-II IgG2 < IgG3; PA OR-II IgG2 < IgG4; q: PA OR-II IgG3 > IgG4; CJ-2002 IgG3 < PA OR-II IgG3; r: PA mixed IgG1 > IgG2; s: PA mixed IgG2 > IgG3; t: PA mixed IgG3 > IgG4. The Student's t-test was used to analyse the differences in mean values, the Chi-square test was used to analyse the difference in prevalence of positive responses. |
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|
Pratt-Riccio et al. Malaria Journal 2008 7:144 doi:10.1186/1475-2875-7-144 |
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