|
Results of analyses which regressed in vitro Plasmodium falciparum growth inhibition against each cross-reactive antibody level. |
||||
| Simple linear regression |
Prais-Winsten's regression |
|||
| half-day†† |
one-day†† |
two-day†† |
||
| (N = 64†) |
(N = 62) |
(N = 50) |
(N = 27) |
|
|
|
||||
| IgM against schizont extract |
R2 = 0.50 (P < 0.0001) |
R2 = 0.43 (P < 0.0001) |
R2 = 0.44 (P < 0.0001) |
R2 = 0.56 (P < 0.0001) |
| IgM against MSP-119 |
R2 = 0.38 (P < 0.0010) |
R2 = 0.16 (P = 0.0016) |
R2 = 0.18 (P = 0.0022) |
R2 = 0.16 (P = 0.036) |
| IgG against szhitont extract |
R2 = 0.22 (P = 0.0001) |
R2 = 0.011 (P = 0.41) |
R2 = 0.026 (P = 0.27) |
R2not obtained (P = 1.0) |
| IgG against MSP-119 |
R2 = 0.029 (P = 0.18) |
R2 = 0.079 (P = 0.063) |
R2 = 0.22 (P = 0.0006) |
R2 = 0.070 (P = 0.18) |
|
Each regression analysis was conducted against single independent variable. †One serum sample (day 6) was not available for antibody measurements and growth inhibition assays. †† For Prais-Winsten's analysis, the data was aggregated in each time-step of half-day, one-day or two-day lengths. | ||||
Nagao et al. Malaria Journal 2008 7:113 doi:10.1186/1475-2875-7-113 |
||||