Malarial pigment haemozoin, IFN-gamma, TNF-alpha, IL-1beta and LPS do not stimulate expression of inducible nitric oxide synthase and production of nitric oxide in immuno-purified human monocytes
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* Corresponding author: Paolo Arese paolo.arese@unito.it
- † Equal contributors
Malaria Journal 2007, 6:73 doi:10.1186/1475-2875-6-73
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Mauro Prato, Valentina Gallo, Giuliana Giribaldi, Paolo Arese Malaria Journal 2008, 7:157 (18 August 2008) Haemozoin-containing trophozoites alters the functionality of human monocytes and macrophages, including an increase in TNF produced. This paper suggests a potential role for matrix metalloproteinases in this pathway.
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