Table 3

Gametocyte prevalence on days 0, 7, 14, 21 and 28 after treatment in patients with adequate parasitological response


Gametocyte prevalence, %, (n/N)




After treatment




At enrolment
Day 7
Day 14
Day 21
Day 28

CQ
4.7 (2/42)
12.5 (3/24)*
4.2 (1/24)*
6.6 (1/15)
0 (0/15)
AQ
12.8 (5/39)
13.1 (5/38)*
10.5 (4/38)*
9.6 (3/31)
0 (0/30)
SP
10.2 (4/39)
44.4 (16/36)
33.3 (12/36)
17.1 (6/35)
6.1 (2/33)
AQ+SP
2.4 (2/83)
3.8 (3/80)*
6.3 (5/80)*
1.3 (1/75)
1.3 (1/75)
AQ+AS
3.6 (3/83)
2.5 (2/80)*
1.2 (1/79)*
1.5 (1/64)
0 (0/64)

CQ, Chloroquine, AQ, amodiaquine; SP, Sulphadoxine-Pyrimethamine; AS, artesunate; 95% CI, 95% confidence interval.

* On day 7 and day 14, significant difference to SP group (P < 0.05)

¶On day 21, significant difference to SP group (P < 0.05)

Ménard et al. Malaria Journal 2007 6:65   doi:10.1186/1475-2875-6-65