Table 2 |
||||
|
Leukocyte aggregation-inducing effects of lipid fractions of Plasmodium vivax paroxysm plasma and of P. vivax schizont extracts with or without supplementation with recombinant human cytokines (TNFα, GM-CSF, IL-6 and IL-10). |
||||
| Expt. No. |
Sample |
% R CAI (Median) |
25% |
75% |
|
|
||||
| 1 |
P1 |
26.30 |
20.10 |
30.60 |
| 2 |
P2 |
4.50 |
3.40 |
8.60 |
| 3 |
P3 |
4.20 |
3.50 |
6.40 |
| 4 |
P4 |
8.50 |
6.80 |
11.80 |
| 5 |
P5 |
1.00 |
0.20 |
1.30 |
| 6 |
P1 + Cytokines |
38.20 |
34.20 |
46.50 |
| 7 |
P2 + Cytokines |
8.70 |
5.60 |
10.90 |
| 8 |
P3 + Cytokines |
8.60 |
4.60 |
12.40 |
| 9 |
P4 + Cytokines |
24.60 |
22.50 |
31.70 |
| 10 |
P5 + Cytokines |
1.20 |
0.50 |
3.60 |
| 11 |
S1 |
3.1 |
1.4 |
6.4 |
| 12 |
S2 |
2.5 |
1.3 |
5.9 |
| 13 |
S3 |
2.9 |
1.2 |
7.4 |
| 14 |
S4 |
14.3 |
12.3 |
18.6 |
| 15 |
S5 |
1 |
0.2 |
2.4 |
| 16 |
S1 + Cytokines |
10.4 |
7.6 |
13.9 |
| 17 |
S2 + Cytokines |
3.8 |
2.5 |
6.4 |
| 18 |
S3 + Cytokines |
2.7 |
1.9 |
6.5 |
| 19 |
S4 + Cytokines |
26.2 |
21.9 |
30.4 |
| 20 |
S5 + Cytokines |
1.1 |
0.3 |
2.1 |
|
|
||||
|
% RCAI: % Relative Cell Aggregation Index (median) 25%–75%: 25th and 75th percentiles Different fractions of P. vivax schizont extracts (S1 – acetone fraction, S2 – ethanol fraction, S3 – petroleum ether fraction, S4 – diethyl ether fraction and S5 – remaining fraction ) and similar fractions of paroxysm plasma ( P1 – acetone fraction, P2 – ethanol fraction, P3 – petroleum ether fraction, P4 – diethyl ether fraction and P5 – remaining fraction ) were tested for their ability to induce cell aggregation with or without supplementation with recombinant human cytokines (TNFα, GM-CSF, IL-6 and IL-10). The table provides the median values together with the interquartile range (25%–75%). |
||||
|
Karunaweera et al. Malaria Journal 2007 6:62 doi:10.1186/1475-2875-6-62 |
||||
