Malaria Journal

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The epidemiology of malaria in adults in a rural area of southern Mozambique

Alfredo Mayor*, John J Aponte, Carole Fogg, Francisco Saúte, Brian Greenwood, Martinho Dgedge, Clara Menendez and Pedro L Alonso

Malaria Journal 2007, 6:3 doi:10.1186/1475-2875-6-3

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Sub-microscopic infections and long-term recrudescence of Plasmodium falciparum in Mozambican pregnant women

Alfredo Mayor, Elisa Serra-Casas, Azucena Bardají, Sergi Sanz, Laura Puyol, Pau Cisteró, Betuel Sigauque, Inacio Mandomando, John J Aponte, Pedro L Alonso, Clara Menéndez Malaria Journal 2009, 8:9 (9 January 2009)

In an area with perennial malaria transmission, sub-microscopic infections are frequent during pregnancy and are not associated with the usual signs of malaria; recrudescences after treatment are not uncommon. Based on these results, the authors suggest that it is important to apply more accurate and sensitive measures to detect malaria during pregnancy and that the follow-up during in vivo therapeutic evaluation of anti-malarial drugs must be extended for longer periods of time.

Research   Open Access

Falciparum malaria and HIV-1 in hospitalized adults in Maputo, Mozambique: does HIV-infection obscure the malaria diagnosis?

Aase Berg, Sam Patel, Nina Langeland, Bjorn Blomberg Malaria Journal 2008, 7:252 (15 December 2008)

The main point of interest of this paper is that the attributable fraction of febrile illness due to malaria is lower in HIV infected adults compared to those who are uninfected. It adds fresh data to this issue.

Research   Open Access

Malaria in rural Mozambique. Part I: Children attending the outpatient clinic

Caterina Guinovart, Quique Bassat, Betuel Sigaúque, Pedro Aide, Jahit Sacarlal, Tacilta Nhampossa, Azucena Bardají, Ariel Nhacolo, Eusébio Macete, Inácio Mandomando, John J Aponte, Clara Menéndez, Pedro L Alonso Malaria Journal 2008, 7:36 (26 February 2008)

An analysis of a total of 94,941 outpatient visits in a rural hospital, of which 30.5% had malaria. The study confirms the logic of targeting preventive measures at children below three years of age, as they carry the highest burden of malaria, but it points out that children aged 5-15 years represent around a third of the malaria cases and should also be included in control programmes.

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Standardizing estimates of the Plasmodium falciparum parasite rate

David L Smith, Carlos A Guerra, Robert W Snow, Simon I Hay Malaria Journal 2007, 6:131 (25 September 2007)

The parasite rate is a commonly reported index of malaria transmission intensity. The analysis of over 140 studies suggests that the relationship between parasite rate and age is predictable across the observed range of malaria endemicity. This new algorithm provides a reliable method for standardizing parasite rate for the purposes of comparing studies and mapping malaria endemicity