Table 1 |
|||
|
Characteristics of study subjects at enrollment |
|||
| Characteristic |
Amodiaquine/Placebo |
Artesunate/Amodiaquine |
|
|
|
|||
| N = 37 (%) |
N = 34 (%) |
||
|
|
|||
| Age (years old) |
Median |
19 |
18.5 |
| Range |
5 to 62 |
3 to 58 |
|
| Gender |
Male |
24 (64.8) |
27 (79.4) |
| Female |
13 (35.2) |
7 (20.6) |
|
| Weight (kg) |
Median |
55 |
57 |
| Range |
19 to 99 |
12.5 to 80 |
|
| Temperature (°C) |
Median |
36.6 |
36.6 |
| Range |
35.9 to 39.0 |
36 to 40.2 |
|
| Parasitaemia (asexual forms/μL) |
Geometric mean |
3420 |
4416 |
| Range |
400 to 34,594 |
480 to 34,594 |
|
| Presence of gametocytes |
Yes |
4 (10.8) |
8 (23.5) |
| No |
33 (89.2) |
26 (76.5) |
|
| Haemoglobin (g/dL) |
Median |
11,6 |
12 |
| Range |
8.3 to 15.3 |
8.0 to 16.3 |
|
| WBC/mm3 |
Median |
5900 |
5200 |
| Range |
2200 to 12800 |
2000 to 15800 |
|
| Neutrophils/mm3 |
Median |
3264 |
2900 |
| Range |
1056 to 7134 |
1210 to 10428 |
|
| Total bilirubin (mg/dL) |
Median |
1 |
1.3 |
| Range |
0.2 to 5.3 |
0.1 to 5.2 |
|
| ALT (U/L) |
Median |
24 |
24.2 |
| Range |
2 to 98 |
5 to 107 |
|
| Creatinine (mg/dL) |
Median |
0.9 |
1 |
| Range |
0.4 to 1.9 |
0.4 to 1.4 |
|
|
|
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|
Osorio et al. Malaria Journal 2007 6:25 doi:10.1186/1475-2875-6-25 |
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