Table 2 |
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|
Prevalence of pfcrt, pfmdr1, dhfr and dhps genotype combinations conferring chloroquine and sulfadoxine-pyrimethamine resistance in Mbeya & Matema, together and each seperated. The risk ratio is the prevalence ratio of the combinations between Mbeya and Matema. |
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| Grouped alleles |
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| Mbeya & Matema (%) |
Mbeya (%) |
Matema (%) |
Risk ratio |
||
|
|
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| Pfcrt+pfmdr1 |
T76+Y86** |
29 (34.1) |
9 (52.9) |
20 (29.4) |
0.5556 |
| Dhfr |
I51+N108* |
80 (93) |
17 (100) |
63 (91.3) |
0.9130 |
| I51+R59* |
71 (82.6) |
16 (94.1) |
55 (79.9) |
0.8469 |
|
| Dhfr triple |
I51+R59+ N108* |
71 (82.6) |
16 (94.1) |
55 (79.7) |
0.8469 |
| Dhps double |
G437+E540*** |
68 (81) |
10 (58.8) |
58 (86.6) |
1.4716 |
| Dhfr/dhps quintuple (triple dhfr + double dhps) *** |
54 (64.3) |
9 (52.9) |
45 (67.2) |
1.2687 |
|
|
|
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|
* N = 86 ** N = 85 *** N = 84 |
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|
Schönfeld et al. Malaria Journal 2007 6:2 doi:10.1186/1475-2875-6-2 |
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