|
Prevalence of mutations conferring resistance to chloroquine, sulfadoxine-pyrimethamine and atovaquone-proguanil in Plasmodium falciparum isolates from Mbeya & Matema, southern Tanzania |
||||
| Gene |
Mutation |
N |
Mutation (%) |
Mixed type (%) |
|
|
||||
| Pfcrt |
T76 |
86 |
37 (43) |
6 (7) |
| Pfmdr1 |
Y86 |
85 |
38 (44.7) |
6 (7.1) |
| Dhfr |
I51 |
86 |
80 (93) |
0 (0) |
| N108 |
86 |
84 (97.7) |
0 (0) |
|
| T108 |
86 |
0 (0) |
0 (0) |
|
| R59 |
86 |
69 (80.2) |
6 (7) |
|
| V16 |
86 |
0 (0) |
0 (0) |
|
| L164 |
86 |
0 (0) |
0 (0) |
|
| Dhps |
A436 |
84 |
4 (4.8) |
3 (3.6) |
| G437 |
84 |
66 (78.6) |
2 (2.4) |
|
| E540 |
84 |
65 (77.4) |
8 (9.5) |
|
| G581 |
81 |
1 (1.2) |
0 (0) |
|
| N613 |
81 |
0 (0) |
0 (0) |
|
| Cytb |
N268 |
85 |
0 (0) |
0 (0) |
Schönfeld et al. Malaria Journal 2007 6:2 doi:10.1186/1475-2875-6-2 |
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