Malaria incidence and efficacy of intermittent preventive treatment in infants (IPTi)
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* Corresponding author: Juergen May may@bni-hamburg.de
Malaria Journal 2007, 6:163 doi:10.1186/1475-2875-6-163
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BioMed Central: 2 citations
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Anne F Gasasira, Moses R Kamya, Edwin O Ochong, Neil Vora, Jane Achan, Edwin Charlebois, Theodore Ruel, Fredrick Kateera, Denise N Meya, Diane Havlir, Philip J Rosenthal, Grant Dorsey Malaria Journal 2010, 9:177 (23 June 2010) The authors used two contemporaneous, very similar, geographically contiguous cohorts of Ugandan children in order to compare malaria incidence in HIV+ children on daily co-trimoxazole (TS) prophylaxis to incidence in HIV-uninfected children not on daily TS. Recrudescence was distinguished from re-infection using molecular methods.
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Jürgen May, Samuel Adjei, Wibke Busch, Julian J Gabor, Saadou Issifou, Robin Kobbe, Benno Kreuels, Bertrand Lell, Norbert G Schwarz, Ohene Adjei, Peter G Kremsner, Martin P Grobusch Malaria Journal 2008, 7:198 (1 October 2008) The observation that the IPTi effect is mainly therapeutic and prophylactic might limit the selection of drugs eligible for IPTi to those that are long-acting. The unique property of SP as an inexpensive, one-dose anti-malaria drug favours SP, provided that it is not used as first line drug for treating malaria in the same area.
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