Table 1

Means of raw and loge-transformed IC50s, geometric means and Geometric Least Squares Means.
1997
 2000
 2001
 2002
 2003
 2004
 Normality
Variable
 N
 Mean
 STD
 N
 Mean
 STD
 N
 Mean
 STD
 N
 Mean
 STD
 N
 Mean
 STD
 N
 Mean
 STD
 p-value
Means (raw values)
CQ
 31
 236
 203.4
 33
 173.2
 223
 31
 251.4
 236.7
 46
 131.3
 104
 34
 143.8
 91.03
 67
 171.5
 157.2
 0.01
QN
 46
 234.6
 150.2
 28
 305.8
 210.4
 31
 444
 286.2
 40
 252.6
 273.6
 34
 280.8
 162.8
 58
 207.5
 149.8
 0.01
MdAQ
 45
 12.8
 12.4
 33
 85.1
 167.8
 31
 57.7
 63.2
 43
 42.9
 32.3
 34
 31.1
 21.3
 64
 21.7
 17.6
 0.01
ART
 10
 3.6
 0.8
 31
 9.8
 12.0
 31
 6.1
 6.6
 40
 5.7
 4.5
 34
 7.4
 5.9
 36
 7.5
 5.0
 0.01
Means (natural log values)
CQ
 31
 4.9
 1.4
 33
 4.4
 1.2
 31
 5
 1.2
 46
 4.5
 0.9
 34
 4.7
 0.8
 67
 4.7
 1
 0.01
QN
 46
 5.2
 0.8
 28
 5.5
 0.8
 31
 5.9
 0.7
 40
 5.1
 0.9
 34
 5.5
 0.5
 58
 5.1
 0.8
 0.04
MdAQ
 45
 2.1
 0.9
 33
 3.8
 1.0
 31
 3.6
 0.9
 43
 3.5
 0.7
 34
 3.2
 0.6
 64
 2.8
 0.9
 0.04
ART
 10
 1.2
 0.3
 31
 1.8
 1.0
 31
 1.3
 1
 40
 1.3
 1.0
 34
 1.8
 0.6
 36
 1.8
 0.7
 0.15
Geometric means
CQ
 31
 130.3
 3.9
 33
 82.3
 3.5
 31
 148.4
 3.2
 46
 93.7
 2.5
 34
 112.2
 2.2
 67
 115.6
 2.7
 -
QN
 46
 181.3
 2.3
 28
 237.5
 2.2
 31
 350.7
 2.1
 40
 169.0
 2.6
 34
 244.7
 1.7
 58
 162.4
 2.1
 -
MdAQ
 45
 8.5
 2.5
 33
 43.8
 2.7
 31
 38.5
 2.4
 43
 33.1
 2.1
 34
 25.3
 1.9
 64
 15.8
 2.4
 -
ART
 10
 3.5
 1.3
 31
 5.8
 2.7
 31
 3.9
 2.7
 40
 3.9
 2.8
 34
 6.1
 1.9
 36
 6.0
 2.0
 -
Geometric Least Squares Means
CQ
 31
 130.8
 1.2
 33
 82.6
 1.2
 31
 148.4
 1.2
 46
 93.3
 1.2
 34
 112.7
 1.2
 67
 115
 1.1
 -
QN
 46
 181.3
 1.1
 28
 238.2
 1.2
 31
 350.1
 1.1
 40
 168.4
 1.1
 34
 245
 1.1
 58
 162.2
 1.1
 -
MdAQ
 45
 8.5
 1.1
 33
 44
 1.2
 31
 38.5
 1.2
 43
 33.1
 1.1
 34
 25.3
 1.2
 64
 15.9
 1.1
 -
ART
 10
 3.5
 1.3
 31
 5.8
 1.2
 31
 3.9
 1.2
 40
 3.9
 1.1
 34
 6.1
 1.2
 36
 6.0
 1.1
 -

P-values are from the Kolmogorov-Smirnov test for normality. CQ = chloroquine; QN = quinine; MdAQ = monodesethylamodiaquine; ART = artemisinin

Vaillant and Olliaro Malaria Journal 2007 6:156   doi:10.1186/1475-2875-6-156

Open Data