Efficacy and safety of artesunate plus amodiaquine in routine use for the treatment of uncomplicated malaria in Casamance, southern Sénégal
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* Corresponding author: Piero L Olliaro olliarop@who.int
Malaria Journal 2007, 6:150 doi:10.1186/1475-2875-6-150
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BioMed Central: 8 citations
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Research
Jean-Louis A Ndiaye, Babacar Faye, Ali Gueye, Roger Tine, Daouda Ndiaye, Corinne Tchania, Ibrahima Ndiaye, Aichatou Barry, Badara Cissé, Valérie Lameyre, Oumar Gaye Malaria Journal 2011, 10:237 (12 August 2011) The paper tackles an important topic as there is a need for continuous evaluation of the safety and efficacy of ACT in malaria endemic areas.
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Philippe Brasseur, Malick Badiane, Moustafa Cisse, Patrice Agnamey, Michel T Vaillant, Piero L Olliaro Malaria Journal 2011, 10:203 (25 July 2011) This is a research article on analysis of routine data from a rural West African dispensary covering the last 15 years, a period of considerable change in malaria control policies.
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Julien Zwang, Piero Olliaro, Hubert Barennes, Maryline Bonnet, Philippe Brasseur, Hasifa Bukirwa, Sandra Cohuet, Umberto D'Alessandro, Abdulaye Djimdé, Corine Karema, Jean-Paul Guthmann, Sally Hamour, Jean-Louis Ndiaye, Andreas Mårtensson, Claude Rwagacondo, Issaka Sagara, Albert Same-Ekobo, Sodiomon B Sirima, Ingrid van den Broek, Adoke Yeka, Walter RJ Taylor, Grant Dorsey, Milijaona Randrianarivelojosia Malaria Journal 2009, 8:203 (23 August 2009) This multi-center analysis study addresses efficacy of artesunate-amodiaquine, a very important candidate for the treatment of uncomplicated malaria globally. The analysis of patient-level data examining the efficacy of AS&AQ compared to local standard therapy, makes a strong case for the use of AS&AQ in all transmission settings.
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Jean Ndiaye, Milijaona Randrianarivelojosia, Issaka Sagara, Philippe Brasseur, Ibrahima Ndiaye, Babacar Faye, Laurence Randrianasolo, Arsène Ratsimbasoa, Doris Forlemu, Vicky Moor, Aminata Traore, Yahia Dicko, Niawanlou Dara, Valérie Lameyre, Mouctar Diallo, Abdoulaye Djimde, Albert Same-Ekobo, Oumar Gaye Malaria Journal 2009, 8:125 (8 June 2009) A carefully-conducted clinical trial presenting a three-armed randomized, non-inferiority, multicentre study of a fixed-dose artesunate-amodiaquine combination either administered once or twice daily compared with standard artemether-lumefantrine treatment during a follow-up duration of 28 days with PCR-corrected cure rates.
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Robin Kobbe, Philipp Klein, Samuel Adjei, Solomon Amemasor, William Thompson, Hanna Heidemann, Maja V Nielsen, Julia Vohwinkel, Benedikt Hogan, Benno Kreuels, Martina Bührlen, Wibke Loag, Daniel Ansong, Jürgen May Malaria Journal 2008, 7:261 (19 December 2008) Numerous trials have demonstrated high efficacy and safety of artemisinin-based combination therapy (ACT) under supervised treatment but looking how these treatments are applied unsupervised are scarce. Unobserved AL and ASAQ treatment showed high adequate clinical and parasitological responses, though AL was inferior in preventing late clinical failures.
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Piero L Olliaro, Henriette Delenne, Moustafa Cisse, Malick Badiane, Alberto Olliaro, Michel Vaillant, Philippe Brasseur Malaria Journal 2008, 7:234 (7 November 2008) This is an interesting analysis of routinely collected health dispensary data on birth weight and pregnancy characteristics in relation to IPTp use.
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Sophie Sarrassat, Paul Senghor, Jean Hesran Malaria Journal 2008, 7:215 (24 October 2008) The paper describes for the first time the morbidity trends in a mesoendemic setting with a relatively low ACT coverage. The findings are relevant to all those involved in malaria control and chemotherapy.
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