Cerebrospinal fluid and serum biomarkers of cerebral malaria mortality in Ghanaian children
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* Corresponding author: Jonathan K Stiles jstiles@msm.edu
Malaria Journal 2007, 6:147 doi:10.1186/1475-2875-6-147
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BioMed Central: 4 citations
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Short Report
Vidhan Jain, Shannon McClintock, Avinash C Nagpal, Aditya P Dash, Jonathan K Stiles, Venkatachalam Udhayakumar, Neeru Singh, Naomi W Lucchi BMC Research Notes 2009, 2:36 (6 March 2009) |
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Research
Glatiramer acetate reduces the risk for experimental cerebral malaria: a pilot study Peter Lackner, Andrea Part, Christoph Burger, Anelia Dietmann, Gregor Broessner, Raimund Helbok, Markus Reindl, Erich Schmutzhard, Ronny Beer Malaria Journal 2009, 8:36 (27 February 2009) A study of role of the host immune response in the pathophysiology of murine cerebral malaria, which may lead to the development of new adjunctive treatment strategies.
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Research
Antibody responses to the merozoite surface protein-1 complex in cerebral malaria patients in India Naomi W Lucchi, Jon Tongren, Vidhan Jain, Avinash C Nagpal, Christian W Kauth, Ute Woehlbier, Hermann Bujard, Aditya P Dash, Neeru Singh, Jonathan K Stiles, Venkatachalam Udhayakumar Malaria Journal 2008, 7:121 (4 July 2008) It remains unclear why only a subset of patients develops cerebral malaria complications, including neurological sequelae or death. This study compares the immune response to MSP in patients with uncomplicated malaria and in CM patients, suggesting that a dysregulation in the generation of antibody may exist during CM.
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Research
Plasma IP-10, apoptotic and angiogenic factors associated with fatal cerebral malaria in India Vidhan Jain, Henry B Armah, Jon E Tongren, Renée M Ned, Nana O Wilson, Sara Crawford, Pradeep K Joel, Mrigendra P Singh, Avinash C Nagpal, AP Dash, Venkatachalam Udhayakumar, Neeru Singh, Jonathan K Stiles Malaria Journal 2008, 7:83 (19 May 2008) An extensive study on biomarkers of inflammation, apoptosis and angiogenesis in children and adults with cerebral malaria in India. A large amount of data is presented that sheds new light on potential mechanisms of CM pathogenesis.
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