Efficacy and safety of artemisinin-based antimalarial in the treatment of uncomplicated malaria in children in southern Tanzania
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* Corresponding author: Abdunoor M Kabanywanyi omulokozi@gmail.com
Malaria Journal 2007, 6:146 doi:10.1186/1475-2875-6-146
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BioMed Central: 5 citations
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Review
The clinical efficacy of artemether/lumefantrine (Coartem®) Michael Makanga, Srivicha Krudsood Malaria Journal 2009, 8(Suppl 1):S5 (12 October 2009) |
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Research
Maryline Bonnet, Ingrid van den Broek, Michel van Herp, Pedro Urrutia, Chantal van Overmeir, Juliet Kyomuhendo, Célestin Ndosimao, Elizabeth Ashley, Jean-Paul Guthmann Malaria Journal 2009, 8:192 (10 August 2009) The finding of varying efficacy of the same combinations at two sites in one country highlights one difficulty of implementing a uniform national treatment policy in a large country. The poor efficacy of AS+AQ in Boende should alert the national programme to foci of resistance and emphasizes the need for systems for the prospective monitoring of treatment efficacy at sentinel sites in the country.
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Research
Robin Kobbe, Philipp Klein, Samuel Adjei, Solomon Amemasor, William Thompson, Hanna Heidemann, Maja V Nielsen, Julia Vohwinkel, Benedikt Hogan, Benno Kreuels, Martina Bührlen, Wibke Loag, Daniel Ansong, Jürgen May Malaria Journal 2008, 7:261 (19 December 2008) Numerous trials have demonstrated high efficacy and safety of artemisinin-based combination therapy (ACT) under supervised treatment but looking how these treatments are applied unsupervised are scarce. Unobserved AL and ASAQ treatment showed high adequate clinical and parasitological responses, though AL was inferior in preventing late clinical failures.
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Review
Zulfiqarali G Premji, Salim Abdulla, Bernhards Ogutu, Alice Ndong, Catherine O Falade, Issaka Sagara, Nathan Mulure, Obiyo Nwaiwu, Gilbert Kokwaro Malaria Journal 2008, 7:244 (25 November 2008) A useful contribution which pulls together data from a number of sources on a question which is constantly raised: whether the African diet is adequate for artemether-lumefantrine absorption.
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Research
Ikeoluwapo O Ajayi, Edmund N Browne, Fred Bateganya, Denis Yar, Christian Happi, Catherine O Falade, Grace O Gbotosho, Bidemi Yusuf, Samuel Boateng, Kefas Mugittu, Simon Cousens, Miriam Nanyunja, Franco Pagnoni Malaria Journal 2008, 7:190 (27 September 2008) A timely report on an ambitious investigation of parasitological cure rates resulting from use of ACTs within the context of HMM in three African countries. This study helps filling the gaps in evidence needed to guide effective implementation of HMM programmes
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