Figure 2.

Prevalence of drug-resistance mutations in Plasmodium falciparum malaria infections in Malawi before and after chloroquine was replaced with sulphadoxine-pyrimethamine in 1993. Chloroquine resistance-conferring T76 mutation in PfCRT (A); Pyrimethamine resistance-conferring C59R mutations in DHFR (B); Adapted from [13] with permission.