Malaria Journal

official impact factor 3.49

Open Access

Spatial and temporal variation in malaria transmission in a low endemicity area in northern Tanzania

MJAM Oesterholt, JT Bousema, OK Mwerinde, C Harris, P Lushino, A Masokoto, H Mwerinde, FW Mosha and CJ Drakeley*

Malaria Journal 2006, 5:98 doi:10.1186/1475-2875-5-98

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BioMed Central: 11 citations

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A cluster-randomized trial of mass drug administration with a gametocytocidal drug combination to interrupt malaria transmission in a low endemic area in Tanzania

Seif A Shekalaghe, Chris Drakeley, Sven van den Bosch, Roel ter Braak, Wouter van den Bijllaardt, Charles Mwanziva, Salimu Semvua, Alutu Masokoto, Frank Mosha, Karina Teelen, Rob Hermsen, Lucy Okell, Roly Gosling, Robert Sauerwein, Teun Bousema Malaria Journal 2011, 10:247 (24 August 2011)

This study illustrates the possibility to achieve high coverage with a three-day MDA intervention, but also the difficulty in defining suitable outcome measures to evaluate interventions in areas of very low malaria transmission intensity.

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Urban malaria and associated risk factors in Jimma town, south-west Ethiopia

Abebe Alemu, Wondewosen Tsegaye, Lemu Golassa, Gemeda Abebe Malaria Journal 2011, 10:173 (24 June 2011)

A cross-sectional malariological survey in Jimma town, south-west Ethiopia, with a descriptive KAP analysis and some risk factors. The paper addresses an issue of public health importance, and the statistics are likely to be of interest to those working in malaria in similar environments.

Research   Open Access

Pattern of malaria transmission along the Rahad River basin, Eastern Sudan

Yousif E Himeidan, Mervet M Elzaki, Eliningaya J Kweka, Muntaser Ibrahim, Ibrahim M Elhassan Parasites & Vectors 2011, 4:109 (16 June 2011)

Along seasonal river basins of eastern Sudan, the number of infective bites due to the malaria vector fluctuates with bimodal annual peaks followed the rainfall and the subsequent recess of the rivers upon its fragmentation into disparate ponds of water. This latter creates adequate breeding habitats, during the hot and cool and dry seasons, for the principal malaria vector, An. arabiensis. Image: Typical breeding sites on the bed of the Al Gash river (an example), Kassala, eastern Sudan.

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Is vaccine the magic bullet for malaria elimination? A reality check

Roma Chilengi, Jesse Gitaka Malaria Journal 2010, 9(Suppl 3):S1 (13 December 2010)

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The impact of human reservoir of malaria at a community-level on individual malaria occurrence in a low malaria transmission setting along the Thai-Myanmar border

Saranath Lawpoolsri, Irwin F Chavez, Surapon Yimsamran, Supalap Puangsa-art, Nipon Thanyavanich, Wanchai Maneeboonyang, Wuthichai Chaimungkun, Pratap Singhasivanon, James H Maguire, Laura L Hungerford Malaria Journal 2010, 9:143 (26 May 2010)

The paper concludes that local malaria control strategies should focus on interventions that aim to reduce the gametocyte carriage in the population, such as early detection and treatment programmes and the use of ACT for P. falciparum.

Research   Open Access

What you see is not what you get: implications of the brevity of antibody responses to malaria antigens and transmission heterogeneity in longitudinal studies of malaria immunity

Samson M Kinyanjui, Philip Bejon, Faith H Osier, Peter C Bull, Kevin Marsh Malaria Journal 2009, 8:242 (28 October 2009)

A major handicap in developing a malaria vaccine is the difficulty in pinpointing the immune responses that protect against malaria. The brevity of antibodies responses makes it difficult to assign the true serological status of an individual at any given time, i.e. those positive at a survey may be negative by the time they encounter the next infection.

Research article   Open Access

Low density parasitaemia, red blood cell polymorphisms and Plasmodium falciparum specific immune responses in a low endemic area in northern Tanzania

Seif Shekalaghe, Michael Alifrangis, Charles Mwanziva, Anders Enevold, Steve Mwakalinga, Humphrey Mkali, Reginald Kavishe, Alphaxard Manjurano, Robert Sauerwein, Chris Drakeley, Teun Bousema BMC Infectious Diseases 2009, 9:69 (21 May 2009)

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Micro-geographic risk factors for malarial infection

Ward P Myers, Andrea P Myers, Janet Cox-Singh, Hui C Lau, Benny Mokuai, Richard Malley Malaria Journal 2009, 8:27 (13 February 2009)

A study designed to evaluate whether geographic parameters are associated with malarial infection in the East Sepik province of Papua New Guinea (PNG), a remote area where malaria is a major cause of morbidity and mortality. Lower elevation and greater distance from administrative centre were noted as risk factors.

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Overuse of artemisinin-combination therapy in Mto wa Mbu (river of mosquitoes), an area misinterpreted as high endemic for malaria

Charles Mwanziva, Seif Shekalaghe, Arnold Ndaro, Bianca Mengerink, Simon Megiroo, Frank Mosha, Robert Sauerwein, Chris Drakeley, Roly Gosling, Teun Bousema Malaria Journal 2008, 7:232 (5 November 2008)

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Dried blood spots as a source of anti-malarial antibodies for epidemiological studies

Patrick H Corran, Jackie Cook, Caroline Lynch, Heleen Leendertse, Alphaxard Manjurano, Jamie Griffin, Jonathan Cox, Tarekegn Abeku, Teun Bousema, Azra C Ghani, Chris Drakeley, Eleanor Riley Malaria Journal 2008, 7:195 (30 September 2008)

Storage of blood drops on various filter paper carriers has been going on for at least 45 years without any clear protocol for storage and conditions for bench life on the immunoglobulin content. This is an important contribution to the field of sero-epidemiology.

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Climate prediction of El Niño malaria epidemics in north-west Tanzania

Anne E Jones, Ulrika Wort, Andrew P Morse, Ian M Hastings, Alexandre S Gagnon Malaria Journal 2007, 6:162 (6 December 2007)

A topic of considerable interest to the climate and health community. It adds further analysis on climate and malaria interactions – a subject already well covered by a number of research groups in East Africa, with the added novelty of an evaluation of seasonal forecasting models.