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Resolution: standard / high Figure 6.
Time average densities. Periodically treated mean values
, (thick/thin) as functions of period 35 <T < 120 for increased initial dose 1.5 <DY < 3.5. Increased DY and frequency 1/T facilitate the onset of drug-resistance (dominant ), e.g. the transition period TR = 30 for DY = 1.5, is shifted towards TR = 49 for DY = 3.5. Dashed lines indicate untreated equilibria for y (thin) and x (thick). The parameter α = 2.06 > α1 assures 'y-domination' for the untreated case.Gurarie and McKenzie Malaria Journal 2006 5:86 doi:10.1186/1475-2875-5-86 |