Table 2 |
||||
|
Frequency of malaria exposed individuals with antibodies of distinct IgG subclass specific for recombinant proteins VIR |
||||
| % of positive sera |
||||
|
|
||||
| IgG |
VIR-A |
VIR-B |
VIR-C |
VIR-E |
|
|
||||
| Subclass |
||||
| IgG1 |
9.5 |
4.8 |
38.6 |
15.0 |
| IgG2 |
14.3 |
0 |
13.6 |
20.0 |
| IgG3 |
14.3 |
4.8 |
15.9 |
25.0 |
| IgG4 |
14.3 |
0 |
11.4 |
0 |
|
|
||||
|
The percentage of responders was calculated as described in the Methods section. The ELISA was performed using subclass-specific, anti-human IgG1, IgG2, IgG3 or IgG4 and serum samples at a dilution of 1:25. Only serum samples that had total IgG specific for proteins VIR were tested in this assay. The cut-off values were defined as the mean plus 3 standard deviation values obtained from 20 uninfected control sera. |
||||
|
Oliveira et al. Malaria Journal 2006 5:83 doi:10.1186/1475-2875-5-83 |
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