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Evaluation of the acquired immune responses to Plasmodium vivax VIR variant antigens in individuals living in malaria-endemic areas of Brazil

Tatiane R Oliveira1 email, Carmen Fernandez-Becerra2 email, Maria Carolina S Jimenez1 email, Hernando A Del Portillo2 email and Irene S Soares1 email

Departamento de Análises Clínicas e Toxicológicas, Faculdade de Ciências Farmacêuticas, Universidade de São Paulo, Av. Prof. Lineu Prestes, 580, 05508-900, São Paulo, SP, Brazil

Departamento de Parasitologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, Av. Prof. Lineu Prestes, 1374, 05508-900, São Paulo, SP, Brazil

author email corresponding author email

Malaria Journal 2006, 5:83doi:10.1186/1475-2875-5-83

Published: 6 October 2006

Additional files

Additional File 1:

Schematic diagram of the IgG antibody response against recombinant VIR proteins in each individual with patent P. vivax malaria. The antibody level was expressed as Index of Reactivity calculated as described in the Methods section. Values of IR ≥ 1.0 were considered as positive. Individuals primary-infected are shown in bold and underlined. Individual responses were categorized as follows: negative individuals (), individuals with IR between 1 to < 2.5 (), individuals with IR between 2.5 to < 5.0 () and individuals with IR ≥ 5.0 ().

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