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Resolution: standard / high Figure 6.
The relationship between sample size (in a single sample) and precision in characterizing
the cure rate is shown; the upper solid line shows the boundary for the cure rate
below which the lower 95% confidence interval bound for the proportion falls below
90%, and the lower dotted line shows the boundary for the cure rate below which the
upper 95% confidence interval bound for the proportion exceeds 90%. Sample sizes to
the left of the curves provide inadequate precision if the objective is to be sure
the confidence interval for the sample does not cross 90%.
Stepniewska and White Malaria Journal 2006 5:127 doi:10.1186/1475-2875-5-127 |