Table 2 |
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|
Performance of PCR relative to expert laboratory microscopy at different Plasmodium falciparum and Plasmodium vivax parasite densities |
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| P. falciparum |
P. vivax |
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|
|
|
|||
| Parasites/μl |
No. detected by microscopya |
No. positive by PCR (%) |
No. detected by microscopya |
No. positive by PCR (%) |
|
|
||||
| >10,000 |
10 |
10 (100.0%) |
3 |
3 (100.0%) |
| 5,000–9,999 |
4 |
4 (100.0%) |
1 |
1 (100.0%) |
| 1,000–4,999 |
22 |
21 (95.5%) |
11 |
11 (100.0%) |
| 500–999 |
11 |
10 (90.9%) b |
5 |
5 (100.0%) |
| 250–499 |
17 |
14 (82.4%) |
19 |
15 (78.9%) |
| 100–249 |
87 |
29 (33.3%) |
57 |
34 (59.6%) |
| 1–<99 |
118 |
24 (20.3%) |
294 |
71 (24.1%) |
| Negative |
8,321 |
96 (1.2%) |
8,200 |
251 (3.1%) |
| Total |
8,590 |
208 (2.4%) |
8,590 |
391 (4.6%) |
|
|
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|
a Data for each parasite includes 4 mixed infections b A single sample was negative for P. falciparum by PCR, however, this sample was positive for P. vivax and P. malariae by PCR |
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|
Coleman et al. Malaria Journal 2006 5:121 doi:10.1186/1475-2875-5-121 |
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