|
Comparison of PCR and expert laboratory microscopy for active malaria surveillance. |
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| No. of samples with the following result by PCR (% of total in row) |
|||||||
|
|
|||||||
| Expert microscopy resμlt |
P. falciparum |
P. vivax |
P. malariae |
P. ovale |
Mixed |
Negative |
Total |
|
|
|||||||
| P. falciparum |
102 (38.4%) |
13 (4.9%) |
0 (0.0%) |
0 (0.0%) |
7 (2.7%) |
143 (54.0%) a |
265 |
| P. vivax |
4 (1.0%) |
131 (33.9%) |
1 (0.3%) |
0 (0.0%) |
8 (2.1%) |
242 (62.7%) b |
386 |
| P. malariae |
0 (0.0%) |
0 (0.0%) |
8 (80.0%) |
0 (0.0%) |
0 (0.0%) |
2 (20.0%) |
10 |
| Mixed |
3 (75.0%) |
0 (0.0%) |
0 (0.0%) |
0 (0.0%) |
1 (25.0%) |
0 (0.0%) |
4 |
| Negative |
70 (0.9%) |
214 (2.7%) |
7 (0.1%) |
2 (<0.1%) |
18 (0.2%) |
7,614 (96.1%) |
7,925 |
| Total |
179 (2.1%) |
358 (4.2%) |
16 (0.2%) |
2 (<0.1%) |
34 (0.40%) c |
8,001 (93.1%) |
8,590 |
|
a 98% (140/143) of microscopy-positive P. falciparum samples that were PCR negative had <250 parasites/μl. b 99% (239/242) of microscopy-positive P. vivax samples that were PCR negative had <250 parasites/μl. c Includes the following mixed infections: 28 P. falciparum/P. vivax, 3 P. vivax/P. ovale, 2 P. vivax/P. malariae and 1 P. falciparum/P. malariae. | |||||||
Coleman et al. Malaria Journal 2006 5:121 doi:10.1186/1475-2875-5-121 |
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