|
Baseline characteristics of study participants, Kindamba, ROC 2004 |
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| AS + AQ |
AS + SP |
Coartem |
Total |
P-value |
|
|
|
|||||
| Number of patients (% of total) |
101 (33.9) |
91 (30.5) |
106 (35.6) |
298 |
|
| Sex: F/M (% F) |
46/55 (45.5) |
38/53 (41.8) |
50/56 (47.2) |
134/164 (45.0) |
P = 0.74 |
| Age* (months) |
20.5 ± 10.7 (7–48) |
23.0 ± 11.9 (6–54) |
36.1 ± 11.1 (12–59) |
26.8 ± 13.2 (12–59) |
P < 0.00 1 |
| Weight*(Kg) |
9.7 ± 2.3 (6–16) |
10.1 ± 2.4 (5–19) |
12.7 ± 2.0 (10–20) |
10.9 ± 2.6 (5–20) |
P < 0.00 1 |
| MUAC* (mm) |
142.5 ± 13.8 (112–180) |
143.5 ± 11.8 (100–188) |
151.5 ± 10.6 (130–190) |
146.1 ± 12.7 (100–190) |
P < 0.00 1 |
| Haemoglobin* (g/dl) |
8.8 ± 1.7 (5.0–12.8) |
9.1 ± 1.7 (5.1–12.3) |
9.6 ± 1.7 (5.1–14.2) |
9.2 ± 1.7 (5.0–14.2) |
P = 0.00 3 |
| Moderate anaemia ‡ (Hgb 5 < 8 g/dl) |
30 (29.7) |
25 (27.5) |
16 (15.2) |
71 (23.9) |
P = 0.03 |
| Mild anaemia ‡ (Hgb 8 < 11 g/dl) |
59 (58.4) |
53 (58.2) |
66 (62.9) |
178 (59.9) |
P = 0.80 |
| Temperature *(°C) |
38.0 ± 1.2 (35.8–40.0) |
37.8 ± 1.3 (34.8–40.7) |
37.9 ± 1.3 (34.8–40.7) |
37.9 ± 1.3 (34.8–40.7) |
P = 0.32 0 |
| Parasite density** (per μl) |
28,941 (2040–200,000) |
24,997 (1200–200,000) |
23,997 (2000–200,000) |
25,890 (1200–200,000) |
P = 0.65 1 |
| Gametocytes ‡ |
23 (22.8) |
24 (26.4) |
9 (8.5) |
56 (18.8) |
P = 0.00 3 |
|
* Values given as mean ± SD (Standard Deviation) and range (min-max value), ** Parasite density given as geometric mean and range. ‡ Anaemia/gametocytemia described by number + proportion of cases with anaemia/gametocytes. | |||||
van den Broek et al. Malaria Journal 2006 5:113 doi:10.1186/1475-2875-5-113 |
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