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Integration and mining of malaria molecular, functional and pharmacological data: how far are we from a chemogenomic knowledge space?

Lyn-Marie Birkholtz1, Olivier Bastien2, Gordon Wells3, Delphine Grando4, Fourie Joubert3, Vinod Kasam5, Marc Zimmermann6, Philippe Ortet7, Nicolas Jacq5, Nadia Saïdani4,8, Sylvaine Roy9, Martin Hofmann-Apitius6, Vincent Breton5, Abraham I Louw1* and Eric Maréchal4*

1 Department of Biochemistry and African Centre for Gene Technologies, Faculty of Natural and Agricultural Sciences, University of Pretoria, 0002, Pretoria, South Africa

2 UMR 5163 CNRS-Université Joseph Fourier, Laboratoire Adaptation et Pathogénie des Microorganismes, Institut Jean Roget, 38700, La Tronche, France

3 Bioinformatics and Computational Biology Unit, Faculty of Natural and Agricultural Sciences, University of Pretoria, 0002, Pretoria, South Africa

4 UMR 5168 CNRS-CEA-INRA-Université Joseph Fourier, Département Réponse et Dynamique Cellulaires; CEA Grenoble, 17 rue des Martyrs, 38054, Grenoble Cedex 09, France

5 Laboratoire de Physique Corpusculaire de Clermont-Ferrand, CNRS-IN2P3, Campus des Cézeaux, 63177 Aubière Cedex, France

6 Department of Bioinformatics, Fraunhofer Institute for Algorithms and Scientific Computing, Schloss Birlinghoven, 53754 Sankt Augustin, Germany

7 Département d'Ecophysiologie Végétale et de Microbiologie; CEA Cadarache, 13108 Saint Paul-lez-Durance, France

8 UMR 5539 CNRS-Université Montpellier II, Place Eugène Bataillon, 34095 Montpellier cedex 05, France

9 Laboratoire de Biologie, Informatique et Mathématiques; Département Réponse et Dynamique Cellulaires; CEA Grenoble, 17 rue des Martyrs, F-38054, Grenoble cedex 09, France

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Malaria Journal 2006, 5:110 doi:10.1186/1475-2875-5-110

Published: 17 November 2006

Additional files

Additional File 1:

Non-redundant malarial structures in the Protein Data Bank (PDB). The table compiles non redundant entries for Plasmodium protein structures in the Protein Data Bank at the date of writing.

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