Thick blood film examination for Plasmodium falciparum malaria has reduced sensitivity and underestimates parasite density
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* Corresponding author: Philip Bejon pbejon@well.ox.ac.uk
Malaria Journal 2006, 5:104 doi:10.1186/1475-2875-5-104
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BioMed Central: 6 citations
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Reliable enumeration of malaria parasites in thick blood films using digital image analysis John A Frean Malaria Journal 2009, 8:218 (23 September 2009) This paper describes the definition and evaluation of a computer-based imaging algorithm for enumeration of malaria parasites in thick films. While still a long way to go from routine use, the accuracy afforded by the technique may be relevant for clinical studies of vaccines or drugs
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Reader technique as a source of variability in determining malaria parasite density by microscopy Wendy O'Meara, Mazie Barcus, Chansuda Wongsrichanalai, Sinuon Muth, Jason D Maguire, Robert G Jordan, William R Prescott, F Ellis McKenzie Malaria Journal 2006, 5:118 (12 December 2006) There is an increased recognition of the lack of consistency in malaria microscopy and this may have implications for clinical malaria trials. The authors believe that training of staff and standardized methods may improve the situation
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