Table 2 |
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Factors facilitating and those hindering the production, dissemination and utilisation of research evidence to guide policy formulation process |
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Factor |
Barrier Factors |
Facilitating Factors |
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Contextual |
-Poverty: (i) Possibility that the drug proposed to replace the existing one may not be cost-effective given the poverty situation facing the majority of the residents (ii) Resource poor government – meagre health budget, high national debt crisis |
-UN agencies e.g. WHO and bilateral agencies e.g. DFID, SDC, USAID, DANIDA etc. readiness to assist technically and financially -Other countries in the Region also changing their national treatment policy |
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Actors/Institutional |
-Fear by drug manufacturers and traders mainly when they still have huge stocks of the drug proposed to be replaced -Perceptions by doctors/clinicians based on their experiences with prescription/use of alternative antimalarial drugs -Perceptions of some biomedical researchers and national level policy decision makers Sometimes contrasting/overlapping research evidence about drug resistance and cure rates of various drugs (lack of/delayed consensus) -Anticipated repercussions about (i) drug's side effects (ii) poor compliance by drug users and sometimes by drug administrators -Sustainability in government health budget should donors pull out/terminate assistance or when external assistance is not guaranteed |
-Involvement of key stakeholders in research -Formation and operation of credible Regional organizations such as EANMAT -Presence formal interface between researchers and policy-makers i.e. institutional and policy frameworks such as TANHERF and professional associations such as national Drug Task Policy Force, MAT, TPHA, and NMAC -Strong local and biomedical research capacity supported by Northern Institutions, bilateral organisations such as DANIDA, DFID, SDC, USAID and multilateral agencies such as TDR |
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Content |
-Cost of alternative drugs -Cost of implementing national policy change -Some studies carried out on too small scale in terms of population sample size and area coverage to justify representation of the national picture -Delay in reporting/disseminating research evidence -Delay in policy-makers to make informed decisions based on research evidence and recommendations -Poor communication of research evidence: some reports being too long, some being too technically/professionally written |
-Availability of local research evidence on drug resistance -Detailed research reports (i) e.g. Abdulla et al. [1] on cost-effectiveness analysis of alternative treatment policy options and Research synthesis (ii) e.g. brief reports to feedback policy-makers |
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Mubyazi and Gonzalez-Block Malaria Journal 2005 4:51 doi:10.1186/1475-2875-4-51 |
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