Table 2 |
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|
Associations with pre-treatment gametocytemia in 126 Ghanaian children with uncomplicated malaria |
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| Factor |
Prevalence of gametocytemia (%) |
Odds ratio (95%CI) of gametocytemia |
|||
|
|
|||||
| Unadjusted |
P |
Multivariate |
P |
||
|
|
|||||
| CQ in blood |
|||||
| None |
27.9 (12/43) |
1 |
1 |
||
| Present |
14.5 (12/83) |
0.4 (0.2–1.2) |
0.07 |
0.3 (0.1–1.0) |
0.04 |
| Ax. temperature |
n.a. |
0.3 (0.1–0.6) |
0.0008 |
0.2 (0.1–0.5) |
0.0009 |
| Parasite density |
|||||
| < 50,000/μL |
26.3 (20/76) |
1 |
1 |
||
| ≥ 50,000/μL |
8.0 (4/50) |
0.2 (0.1–0.8) |
0.01 |
0.2 (0.1–0.8) |
0.02 |
| dhfr triple mutation |
|||||
| Absent |
10.4 (7/67) |
1 |
1 |
||
| Present |
28.8 (17/59) |
3.5 (1.2–10.2) |
0.009 |
3.2 (1.0–10.4) |
0.049 |
| crt 76 mutation |
|||||
| Absent |
4.0 (1/25) |
1 |
1 |
||
| Present |
22.8 (23/101) |
7.1 (1.0–304) |
0.04 |
14.5 (1.4–150.8) |
0.02 |
|
|
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|
Ax., axillary; n.a., not applicable |
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|
Mockenhaupt et al. Malaria Journal 2005 4:42 doi:10.1186/1475-2875-4-42 |
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