Malaria Journal

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Data mining of the transcriptome of Plasmodium falciparum: the pentose phosphate pathway and ancillary processes

Zbynek Bozdech and Hagai Ginsburg*

Malaria Journal 2005, 4:17 doi:10.1186/1475-2875-4-17

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Co-ordinated stage-dependent enhancement of Plasmodium falciparum antioxidant enzymes and heat shock protein expression in parasites growing in oxidatively stressed or G6PD-deficient red blood cells

Oscar Akide-Ndunge, Elisa Tambini, Giuliana Giribaldi, Paul J McMillan, Sylke Müller, Paolo Arese, Francesco Turrini Malaria Journal 2009, 8:113 (29 May 2009)

Abstract | Full text | PDF | PubMed | Editor’s summary

A study of the expression of antioxidant enzymes and heat shock proteins of infected red blood cells under normal and oxidative conditions. Exogenous oxidative stress or cultivation of parasites in G6PD-deficient RBCs resulted in enhanced transcription and expression of all genes tested. The outstanding finding of this investigation is that the expression of Hsps was redox-responsive.

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Quantitative protein expression profiling reveals extensive post-transcriptional regulation and post-translational modifications in schizont-stage malaria parasites

Bernardo J Foth, Neng Zhang, Sachel Mok, Peter R Preiser, Zbynek Bozdech Genome Biology 2008, 9:R177 (17 December 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | Editor’s summary

A quantitative time-course analysis of protein abundance for Plasmodium falciparum schizonts using two-dimensional differential gel electrophoresis reveals significant post-transcriptional regulation.

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