Antioxidant defense in Plasmodium falciparum – data mining of the transcriptome
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* Corresponding author: Hagai Ginsburg hagai@vms.huji.ac.il
Malaria Journal 2004, 3:23 doi:10.1186/1475-2875-3-23
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BioMed Central: 5 citations
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Research
Oscar Akide-Ndunge, Elisa Tambini, Giuliana Giribaldi, Paul J McMillan, Sylke Müller, Paolo Arese, Francesco Turrini Malaria Journal 2009, 8:113 (29 May 2009) A study of the expression of antioxidant enzymes and heat shock proteins of infected red blood cells under normal and oxidative conditions. Exogenous oxidative stress or cultivation of parasites in G6PD-deficient RBCs resulted in enhanced transcription and expression of all genes tested. The outstanding finding of this investigation is that the expression of Hsps was redox-responsive.
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Research
Bernardo J Foth, Neng Zhang, Sachel Mok, Peter R Preiser, Zbynek Bozdech Genome Biology 2008, 9:R177 (17 December 2008) A quantitative time-course analysis of protein abundance for Plasmodium falciparum schizonts using two-dimensional differential gel electrophoresis reveals significant post-transcriptional regulation. |
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Research article
Onguma Natalang, Emmanuel Bischoff, Guillaume Deplaine, Caroline Proux, Marie-Agnès Dillies, Odile Sismeiro, Ghislaine Guigon, Serge Bonnefoy, Jintana Patarapotikul, Odile Mercereau-Puijalon, Jean-Yves Coppée, Peter H David BMC Genomics 2008, 9:388 (18 August 2008) |
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Software
YANA – a software tool for analyzing flux modes, gene-expression and enzyme activities Roland Schwarz, Patrick Musch, Axel von Kamp, Bernd Engels, Heiner Schirmer, Stefan Schuster, Thomas Dandekar BMC Bioinformatics 2005, 6:135 (1 June 2005) |
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Research
Zbynek Bozdech, Hagai Ginsburg Malaria Journal 2005, 4:17 (18 March 2005) In order to be useful, the huge amount of transcriptomic data now available for malarial parasites needs to be linked to already available biochemical and functional data. This was done here for the pentose phosphate pathway of carbohydrate metabolism.
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