Table 2 |
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|
Adjusted odds ratio (OR) of the probability of gametocyte prevalence, using a multivariate random effect logistic model for untreated and SP-treated children separately. |
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| Risk factors for gametocytaemia |
Adjusted OR (95% CI) |
||
|
|
|||
| No treatment |
Treatment with SP |
||
|
|
|||
| Day of follow-up |
Day 7 |
1.48 (0.62 – 3.56)¥ |
1.77 (0.93–3.34)¥ |
| Day 14 |
1 (ref) |
1 (ref) |
|
| Age |
<5 years |
6.34 (1.15–34.90) |
5.38 (1.91–15.17) |
| 5–9 years |
3.07 (0.98–9.55)¥ |
3.22 (1.19–8.72) |
|
| 10–16 years |
1 (ref) |
1 (ref) |
|
| Asexual parasite density at enrolment |
Per 100 parasites/μl |
1.05 (1.00–1.11) |
1.01 (1.00–1.01) |
| Gametocyte prevalence at enrolment |
Present |
3.35 (1.22–9.18) |
4.12 (2.11–8.02) |
| Absent |
1 (ref) |
1 (ref) |
|
| SP treatment outcome |
R2/3 resistance |
- |
3.40 (1.61–7.19) |
| Rl resistance |
- |
1.06 (0.45–2.47)¥ |
|
| Adequate response |
- |
1 (ref) |
|
|
|
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|
Adjusted = adjusted for all other variables in the model, OR = odds ratio, CI = confidence interval, ref = reference group, ¥ = not statistically significant, - = not applicable. A GEE model was used to allow for correlation between observations from the same individuals. Children reporting the use of antimalarial drugs prior to enrolment were excluded from these analyses. |
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|
Bousema et al. Malaria Journal 2004 3:18 doi:10.1186/1475-2875-3-18 |
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