Table 7

Correlation of EST abundance and microarray intensity associated with SERA gene family

Gene (Locus name)

EST count^a

Comments ^b

Microarray intensity values ^c

Miller et al. [42]

Le Roch et al. [43]

Bozdech et al. [19]

Wu et al. [44]

R

T

S

T

S

Asyn

SERA8 (PFB0325c)

-

-/+

35.3

10.4

39.3

-

-

179

SERA7 (PFB0330c)^d

7

-/+

160.5

982.1

1298

2238

5475.83

2415

SERA6 (PFB0335c) ^e

2

+

200.7

588.6

1012.6

1695.17

4802.83

3428

SERA5 (PFB0340c) ^{e, f}

98

+

1255.4

4623.7

10265.5

13253.67

59511.17

28613

SERA4 (PFB0345c) ^e

4

+

200

496.7

1456.7

3115.17

10053.17

2273

SERA3 (PFB0350c)

-

+

87.3

341

579.7

-

6319.83

4572

SERA2 (PFB0355c)

-

-/+

185.4

219.4

399.1

-

-

1401

SERA1 (PFB0360c)

2

-/+

125.9

178.1

615.7

-

-

376

^a -, no ESTs observed. ^b Comments on gene expression: -/+, low or absent expression; +, expression confirm by RT-PCR and microarray. ^c R, Rings; T, Trophozoite; S, Schizont; Asyn, asynchronous culture; -, No expression value reported. ^d EST count of TIGR TC7227. ^e Central genes in the SERA locus that could not be disrupted in study [42]. ^f Gene with multiple transcripts, TC6886 (BI670678) TC6962 (BI814535).

Isokpehi and Hide Malaria Journal 2003 2:38   doi:10.1186/1475-2875-2-38