Email updates

Keep up to date with the latest news and content from Malaria Journal and BioMed Central.

Open Access Commentary

Unexpected detection of Plasmodium vivax and Plasmodium falciparum DNA in asymptomatic blood donors: fact or artifact?

Alfredo Mendrone1, Crispim Cerutti2, José Eduardo Levi14*, Marcos Boulos3, Maria Carmen Arroyo Sanchez4, Rosely dos Santos Malafronte4, Silvia Maria Di Santi45 and Vicente Odone1

Author Affiliations

1 Fundação Pró-Sangue, Hemocentro de São Paulo, São Paulo, Brazil

2 Unidade de Medicina Tropical, Universidade Federal do Espírito Santo, Vitoria, Brazil

3 Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil

4 Instituto de Medicina Tropical, Universidade de São Paulo, São Paulo, Brazil

5 Superintendência de Controle de Endemias, Secretaria de Estado da Saúde de São Paulo, São Paulo, Brazil

For all author emails, please log on.

Malaria Journal 2014, 13:336  doi:10.1186/1475-2875-13-336

Published: 28 August 2014

Abstract

A study searching for Plasmodium vivax and Plasmodium falciparum DNA among blood donors from the non-endemic area in Brazil reported a rate of 7.41%. This number is at least three times higher than what has been observed in blood donors from the Amazon, an endemic area concentrating >99% of all malaria cases in Brazil. Moreover, the majority of the donors were supposedly infected by P. falciparum, a rare finding both in men and anophelines from the Atlantic forest. These findings shall be taken with caution since they disagree with several publications in the literature and possibly overestimate the actual risk of malaria transmission by blood transfusion in São Paulo city.