Malaria Journal

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A theoretical approach to predicting the success of genetic manipulation of malaria mosquitoes in malaria control

Christophe Boëte* and Jacob C Koella

Malaria Journal 2002, 1:3 doi:10.1186/1475-2875-1-3

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Review   Open Access Highly Accessed

Mathematical models of malaria - a review

Sandip Mandal, Ram Sarkar, Somdatta Sinha Malaria Journal 2011, 10:202 (21 July 2011)

A timely review article that aims to assess the current state of the malaria modelling field, predominantly focusing on mathematical (rather than statistical) models.

Research article   Open Access

Rodent malaria-resistant strains of the mosquito, Anopheles gambiae, have slower population growth than -susceptible strains

Maarten J Voordouw, Bradley R Anholt, Pam J Taylor, Hilary Hurd BMC Evolutionary Biology 2009, 9:76 (20 April 2009)

Research   Open Access Highly Accessed

Effect of larval crowding on mating competitiveness of Anopheles gambiae mosquitoes

Kija R Ng'habi, Bernadette John, Gamba Nkwengulila, Bart GJ Knols, Gerry F Killeen, Heather M Ferguson Malaria Journal 2005, 4:49 (30 September 2005)

The success of the release of sterile or transgenic Anopheles for malaria control depends on their mating competitiveness within wild populations. The discovery that males from un-crowded larval rearing conditions mated before males reared under more crowded conditions, has important implications in this context.

Research   Open Access Highly Accessed

Host genotype by parasite genotype interactions underlying the resistance of anopheline mosquitoes to Plasmodium falciparum

Louis Lambrechts, Jean Halbert, Patrick Durand, Louis C Gouagna, Jacob C Koella Malaria Journal 2005, 4:3 (11 January 2005)

Transmission of malaria is influenced both by the vector competence of the mosquito and the genotype of the parasite. When envisaging the release of GM-mosquitoes, what counts is not so much the release of refractory females that are resistant to all wild parasites, as the release of males that would out-compete the wild-type in mating and give rise to F1 females that are resistant to all wild parasites.

Methodology   Open Access

MalariaSphere: A greenhouse-enclosed simulation of a natural Anopheles gambiae (Diptera: Culicidae) ecosystem in western Kenya

Bart GJ Knols, Basilio N Njiru, Evan M Mathenge, Wolfgang R Mukabana, John C Beier, Gerry F Killeen Malaria Journal 2002, 1:19 (18 December 2002)

Research   Open Access Highly Accessed

Behavioural determinants of gene flow in malaria vector populations: Anopheles gambiae males select large females as mates

FM Okanda, A Dao, BN Njiru, J Arija, HA Akelo, Y Touré, A Odulaja, JC Beier, JI Githure, G Yan, LC Gouagna, BGJ Knols, GF Killeen Malaria Journal 2002, 1:10 (14 August 2002)

Opinion   Open Access Highly Accessed

Advantages of larval control for African malaria vectors: Low mobility and behavioural responsiveness of immature mosquito stages allow high effective coverage

Gerry F Killeen, Ulrike Fillinger, Bart GJ Knols Malaria Journal 2002, 1:8 (21 June 2002)